Reactive vaccination campaigns (RVCs)
All RVCs are approved by the International Coordinating Group on Vaccine Provision (ICG) and supported by Gavi, the Vaccine Alliance.
Niger
The most recent ICG approval was on 24th October 2022. This will support an outbreak response in 3 districts in Niger: Keita, Madoua and Tchirozerine. The response will aim to protect about 1.2 million people (from the age of 9 months to 60 years).
This outbreak response was triggered by the notification of YF cases in these three districts, with dates of onset from June through to August 2022. The situation is made more complex by the circulation of Hepatitis E in some parts of country; an infection that can have similar clinical features to yellow fever.
The country has received the vaccine and devices and is progressing with plans to implement in late November 2022.
Central African Republic (CAR)
CAR has been experiencing an outbreak of yellow fever since late 2021, with a total of 22 confirmed cases. The most recently confirmed case date is 14th March 2022. (There are several delays in recent laboratory results).
The country was endorsed by the ICG for a response in March 2022, that would protect approximately 475,000 people in three districts: Batangafo-Kabo, Haut Mbombou and Nangha-Boguila.
As part of the outbreak response, a first yellow fever RVC was launched on 13th July 2022 and completed in September. Delays were due to logistical and security constraints.
The Bambari and Kembe Satema YF RVCs were launched in early November. Security problems occurred in both health districts. The two YF RVCs seek to protect approximately 736,727 people.
Preventive mass vaccination campaigns (PMVCs)
Uganda
Uganda has now completed the rollout of YF vaccine into its routine immunization (RI) programme. This is a great achievement for the EYE Strategy, as Uganda is the second of four countries that were pending to introduce YF into their RI from the start of the Strategy.
A multi-year PMVC is also planned to launch in upcoming weeks and due to run in three phases over 3 years. This will mark a significant step towards protecting the population against the disease. The aim is to target 12 million people in the 2022 phase of the campaign.
The Democratic Republic of the Congo (DRC)
The proposed dates for launching the YF PMVCs are as follows: Sud Kivu - 24th November; Sankuru - 28th November and Maniema - 1st December 2022.
Further YF PMVCs are planned in Lomami, Kasai, East Kasai and Central Kasai for early 2023. Overall, the campaigns will aim to protect around 28 million people.
Nigeria
Activities in Ogun and Gombe states were completed in June. The PMVC is now being implemented in Borno, Kano, Enugu, and Adamawa, with the campaign in Bayelsa state being postponed until the first quarter of 2023 due to significant floods in the state.