"SAGE’s review concluded that a single-dose Human Papillomavirus (HPV) vaccine delivers solid protection against HPV, the virus that causes cervical cancer, that is comparable to 2-dose schedules. This could be a game-changer for the prevention of the disease; seeing more doses of the life-saving jab reach more girls.
SAGE recommends updating dose schedules for HPV as follows:
one or two-dose schedule for the primary target of girls aged 9-14
one or two-dose schedule for young women aged 15-20
Two doses with a 6-month interval for women older than 21"
In developing countries, limited access to effective screening means that the disease is often not identified until it is further advanced and symptoms develop. In addition, prospects for treatment of such late-stage disease may be poor, resulting in a higher rate of death from cervical cancer in these countries. The high mortality rate from cervical cancer globally (52%) could be reduced by effective screening and treatment programmes.
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